Bulletin Board

Physicians' offices invited to become research sites and enroll patients

Monrovia, Calif. (July 13, 2016) – InSource Diagnostics announced today that it is enlisting research sites to enroll patients in the SPHERE Registry for a clinical trial designed to validate biomarkers in urine that predict genetic mutations, which affect a patient's ability to properly metabolize medications.

ALERT: The FDA is alerting the public, health care providers, lab personnel, and lab test developers that biotin can significantly interfere with certain lab tests and cause incorrect test results which may go undetected. Many lab tests use iummunoassay tests that incorporate biotin technology due to its ability to bond with specific proteins which can be measured to detect certain health conditions. FDA Warning: https://www.fda.gov/MedicalDevices/Safety/AlertsandNotices/ucm586505.htm

D.B Kassel1,2, Michael Rummel2, Sky Countryman2
1SciAnalytical Strategies, Inc., 505 Coast Blvd. South, La Jolla, CA 92037 and 
2InSource Diagnostics, Inc., 231 Chestnut Ave., Monrovia, CA 91016

With the ever increasing sensitivity of high performance triple quadrupole and QTOF mass spectrometers, quantification of most drugs (non-biological) does not require large  volumes of collected blood or serum but convention dictates large blood volume collection by trained phlebotomists.

Justin Wotring, BS, CLS, MLS (ASCP), Eric Kozial, BS, Michael Rummel, BS InSource Diagnostics, Monrovia, CA

When analyzing urine specimens for pain management compliance, it is important to identify any illicit substances that may put both the patient and physician at risk. The detection of an illicit substance in a patient undergoing a pain management regimen may result in dismissal from the program and discontinuation of prescribed medications.

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