CRP (non Cardiac)
Test Code: 4528CPT: 86140
|Tests Included||C-Reactive Protein|
|Use||Measurement of CRP is useful for the detection and evaluation of infection, tissue injury, inflammatory disorders and associated diseases.
Measurements may also be useful as an aid in the identification of individuals at risk for future cardiovascular disease. C-reactive protein (CRP) has long been recognized as one of the most, if not the most, sensitive of the acute-phase reactants.
|Clinical Utility||C-reactive protein levels in plasma can rise dramatically after myocardial infarction, stress, trauma, infection, inflammation, surgery, or neoplastic proliferation. The increase occurs within 24 to 48 hours, and the level may be 2000 times normal. Because the increase is nonspecific however, it cannot be interpreted without a complete clinical history, and even then only by comparison with previous values. For unknown reasons, the degree of C-reactive protein response varies in some diseases that are otherwise apparently similar. For example, the C-reactive protein response in systemic lupus and ulcerative colitis, even when there are obvious signs and symptoms of inflammation, is slight in contrast to its very large response in rheumatoid arthritis and Crohn's disease.|
|Intended Patient Population||18+ and Older Adult Males & Females|
|Patient Preparation||None Specified|
|Tube||Red, Green, Tiger|
|Volume||4mL Whole Blood (1mL Serum/Plasma)|
|Min Sample Volume||0.5 mLs|
|Reference Ranges||M & F ≥ 18 yrs old; < 5 mg/L|
|Analytical Measurement Range||5-300 mg/L|
|Test Turnaround Time||1 Day|
|Specimen Stability||7 Days RF|
|Reject Criteria||Gross Hemolysis|
|Laboratory Developed Test (LDT)||Yes|
|References||1. Ashwood, E.R., Burtis, C.A., Tietz Textbook of Clinical Chemistry, 2nd Edition, W.B. Saunders, 1994.
2. Rose, N.R. et. al (ed) Manual of Clinical Laboratory Immunology, American Society of Microbiology, Washington, DC, 1986