Common Interferences with POCT Cups

Common Interferences with POCT Cups

CLIA waived point-of-care devices are a critical component of a Risk Assessment Program. However, there are common interferences that can cause false positives on POCT (point-of-care testing) cups.

 

Drug Class Drug Trade Name
Amphetamines/
Methamphetamine
Amantadine Symmetrel®
Brompheniramine Dimetane®
Bupropion Wellbutrin®, Zyban®, Voxra®, Budeprion®
Chlorpromazine Thorazine®, Largactil®
Desipramine Norpramin®, Pertofrane®
Diphenhydramine Benadryl®
Doxylamine Unisom®
Ephedrine Ephedra®, Ma Huang®
Isoxsuprine Duvadilan®
Labetolol Labetalol®, Trandate®
Methylphenidate Ritalin®
Mexiletine Mexitil®
Phentermine Adipex®/Obenix®/Oby-Trim®
Phenylephrine Frenin®, Nefrin Eye®
Phenylpropanolamine Propalin®, Proin®
Propranolol Inderal®
Pseudoephedrine Claritin-D®, Sudafed®
Ranitidine Zantac®
Trazodone Desyrel®, Oleptro®, Deprax®, Desirel®
Trimipramine Surmontil®, Rhotrimine®, Stangyl®
Tyramine Tyramine®
Barbituates Phenytoin Dilantin®
Primidone Mysoline®
NSAIDS Aspirin, Advil®, Motrin®, Tylenol®
Benzodiazepines Oxaprozin Daypro®
Sertaline Zoloft®
Marijuana Efavirenz Sustiva®
NSAIDS Aspirin, Advil®, Motrin®, Tylenol®
Proton-pump inhibitors Prilosec®, Prevacid®, Nexium®, Protonix®
Methadone Chlorpromazine Thorazine®
Clomipramine Anafranil®
Diphenhydramine Benadryl®
Doxylamine Unisom®
Quetiapine Seroquel®
Verapamil Isoptin, Verelan®
Opiates Detromethorphan Robitussin DM®
Diphenhydramine Benadryl®
Levofloxacin Levaquin®
Quinine Tonic Water
Quinolones Avelox®, Cipro®, Levaquin®
Rifampin Rimactine®, Rifadin®, Rofact®
Phencyclidine Dextromethorphan Robitussin DM®, Mucinex DM®, NyQuil®
Diphenhydramine Benadryl®
Doxylamine Unisom®
Ibuprofin Advil®/Motrin®
Imipramine Tofranil®, Deprimin®, Deprinol®
Ketamine Ketanest®, Ketaset®, Ketalar®
Tramadol Ryzolt®, Ultram®
Venlafaxine Effexor®

 

References Baden LR, et al. JAMA. 2001; 286:3115-9. Shults TF. Medical Review Officer Handbook. 8th ed. 2002. Zacher JL, et al. Annual Pharmacotherapy. 2004; 38:1525-8.